Management of a holding protocol 2025

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The IACUC shall review and approve, require modifications in (to secure approval), or withhold approval of activities related to the care and use of animals. The IACUC procedures for protocol review are detailed in the proceeding policy. IACUC protocols are to be completed and submitted electronically to the IACUC.
The IACUC oversees the specific use of animals by formally reviewing animal use protocols and granting approval prior to the work commencing. The 2 valid methods of protocol review are either full committee review (FCR) or designated member review (DMR). (PHS Policy IV. C.
Animal management is centred around the responsible care and management of animals; it requires a high degree of knowledge and skill, to ensure the wellbeing of any critters under your care.
Review Process New protocol submissions are reviewed by either designated member or full committee review (FCR). Designated reviews are completed by at least one IACUC member. Full committee review (FCR) involves primary and secondary reviewers presenting to the full committee at a convened committee meeting.
The IACUC Protocol Review Criteria Provide written assurance that the proposed activities do not unnecessarily duplicate previous experiments. Use procedures that avoid or minimize discomfort to animals. Consider alternatives to procedures that may cause more than momentary or slight pain or distress to the animals.
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Each animal protocol must include: (1) a justification for using animals, the number of animals to be used, and the species chosen, (2) the procedures or drugs to be used to eliminate or minimize pain and discomfort, (3) a description of the methods and sources used to search for alternatives to painful procedures, and
All amendments to the protocol must be approved prior to implementation (see IACUC Policy Review and Approval of Protocol Amendments). Any time an animal is euthanized for the purpose of using their tissues, or any time project-specific antemortem manipulation is involved, IACUC review and approval is required.
The IACUC meets semi-annually and at other times as needed. The functions of the committee include: Reviewing annually the Universitys program for humane care and use of animals and inspecting semi-annually all of the Universitys animal facilities.

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