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The BMBL describes combinations of microbiological practices, laboratory facilities, and safety equipment in combination with four biosafety levels for various agents infectious to humans. The descriptions of biosafety levels (BSL) 1 4 parallel those in the NIH Guidelines for research involving recombinant DNA.
BSL-2 (Moderate Level): Agents: Associated with human diseases, but vaccines or treatments are often available. Containment: BSL-1 measures plus restricted access, biohazard warning signs, and additional protective equipment. Work is typically performed in a biological safety cabinet.
Biosafety level 4 laboratories are used for diagnostic work and research on easily transmitted pathogens which can cause fatal disease. These include a number of viruses known to cause viral hemorrhagic fever such as Marburg virus, Ebola virus, Lassa virus, and Crimean-Congo hemorrhagic fever.
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