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Azo- and benzidene-based substances

Azo- and benzidene-based substances 2025

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The document is a Stakeholder Interest Form for companies interested in Aromatic Azo- and Benzidine-Based Substances. It allows stakeholders to declare their interest, provide identification details, request confidentiality for submitted information, and share relevant data about the substances they are involved with. The form aims to facilitate communication between stakeholders and the Government of Canada regarding future decisions on these substances.

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What foods contain benzidine?

Only rarely has benzidine been detected in areas other than waste sites, and it has not been found in food. Some dyes used to color foods or drinks may contain impurities that can be broken down to benzidine once inside the body.

What dyes are metabolized to benzidine?

Three dyes that would be metabolized to benzidine, Direct Black 38, Direct Blue 6 and Direct Brown 95, were tested for carcinogenicity by oral administration (feed or drinking-water) or bladder implantation.

What does benzidine do to your body?

Benzidine can cause cancer. This has been shown in studies of workers who were exposed for many years to levels much higher than the general population would experience. It is important to note that most of the workers did not develop cancer, even after such high exposures.

What is an example of benzidine?

Benzidine derivatives, such as 3,30-dimethylbenzidine and 3,30-dimethoxybenzidine (o-dianisidine) (Figure 25), are used as dyes or intermediates for dyestuffs or pigments (e.g., Trypan Blue, Acid Red 14, Direct Blue 1, 8, 15, 76, 98, 218, and Pigment Orange 16), coatings, plastics, or in chemical studies.

What products contain benzidine?

Benzidine-based dyes are used in the production of textiles, paints, printing inks, paper, and pharmaceuticals. They are also used as reagents and biological stains in laboratories, and have more recent uses in laser, liquid crystal displays, ink-jet printers, and electro-optical devices.

What products have benzidine?

Benzidine-based dyes are used in the production of textiles, paints, printing inks, paper, and pharmaceuticals.

Where do you find benzidine?

Benzidine is a manufactured chemical that does not occur in nature. In the past, large amounts of benzidine were used to produce dyes for cloth, paper, and leather. It was also used in clinical laboratories for detecting blood, as a rubber-compounding agent, and in the manufacture of plastic films.

Are benzene and benzidine the same?

Benzidine is a diamine, manufactured as synthetic aromatic hydrocarbon with two benzene rings covalently bonded to one another (1,1), substituted by amino group at 4,4.

Azo- and benzidene-based substances 2025

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