FORM TYPE: VWD 2025

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Von Willebrand disease (VWD) is a blood disorder in which the blood does not clot properly. VWD is the most common bleeding disorder. Signs of VWD include nosebleeds, easy bruising, heavy menstrual bleeding, and longer than normal bleeding after injury, surgery, dental work, or childbirth.
Type 2: This is an autosomal dominant disease caused by several qualitative defects in von Willebrand factor. It has four subtypes (2A-AD or AR, 2B-AD, 2N-AR, 2M-AD). 2A is the most common variant. Type 3: This is an autosomal recessive disease (AR) and is caused by a complete quantitative defect.
Are there different types of VWD? Type 1 VWD: VWF are lower than normal (
Type 3 VWD is found in 5%-10% of patients. People with type 3 VWD have a very low levels or no VWF in their blood.. Some people with this type of VWD may also be low in factor VIII (factor eight). Symptoms are typically severe, and include spontaneous bleeding episodes, often into their joints and muscles.