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FLE09 Protocol version2 - Fondazione FIL - filinf

FLE09 Protocol version2 - Fondazione FIL - filinf 2025

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The document outlines a clinical protocol for a phase II trial conducted by the Intergruppo Italiano Linfomi (IIL) to evaluate the efficacy and safety of a brief chemoimmunotherapy regimen combining Rituximab, Bendamustine, and Mitoxantrone in elderly patients (aged 65-80) with advanced stage follicular lymphoma. The study aims to demonstrate a promising complete remission rate and assess progression-free survival, molecular response rates, and overall survival compared to historical data. It includes detailed sections on study design, objectives, treatment plans, inclusion/exclusion criteria, and safety assessments.

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