Tutorial on Diagnostic Cytopathology 2025

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There are two main kinds, or branches, of cytology: exfoliative cytology and intervention cytology. Healthcare providers can use cytology tests for almost all areas of your body. Some common types of cytology tests include: Gynecologic cytology.
Diagnostic Cytology is a specialist discipline that includes examination of diagnostic and screening samples collected using non-invasive and minimally invasive techniques to confirm or exclude disease.
Cytology allows the diagnosis of malignancy from a small number of cells. Cervical Pap smears are the most recognised example of this kind of testing and have dramatically reduced the incidence of squamous cervical carcinoma.
Some of the ways a provider can collect cytology test samples include: Brushing or scraping tissue from the surface of a part of your body. Collecting fluid or discharge samples from your body, such as a pee sample. Using fine-needle aspiration to draw a fluid sample from an area in your body.
[1,4] The science of cytopathology is currently well standardized with two major branches, exfoliative and aspiration biopsy.
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Cytology is the exam of a single cell type, as often found in fluid specimens. Its mainly used to diagnose or screen for cancer. Its also used to screen for fetal abnormalities, for pap smears, to diagnose infectious organisms, and in other screening and diagnostic areas.
Diagnostic cytology is a specialist discipline that provides the examination of samples taken by non-invasive or minimally invasive procedures. This is done by examining cells from fluids, brushings or fine needle aspirates (FNAs) to give a diagnosis of disease.

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