Animal Care and Use Protocol Form - Tuskegee University 2025

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An Animal Care and Use Protocol is a request made to the Institutional Animal Care and Use Committee (IACUC) to conduct a scientific experiment on live, vertebrate animals.
Each protocol must be reviewed annually and must take into consideration changes in standards and guidelines, and developments in the replacement, reduction, and refinement of experimental animal use.
The IACUC review of protocols requires an assurance that the animal model is appropriate and that the proposed experimental design uses the appropriate number of animals in a manner likely to achieve the scientific objectives of the study.
IACUC approved Animal Protocols must undergo complete review (i.e. de novo) at least once every three years (PHS Policy, IV. C. 5.).
Question: What are the two principal animal research regulatory documents used by the Office of Laboratory Animal Welfare (OLAW)? The PHS Policy on Humane Care and Use of Laboratory Animals and the USDA Animal Welfare Regulations (AWR).

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The three year limit on animal protocols is explicitly stated in the federal regulations. Extensions cannot be given for any reason. You must submit a new protocol for review and approval.

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