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The document outlines the concept of reproductive toxins, classified as substances that can adversely affect reproductive capabilities. It details four categories: mutagens, teratogens, sterility/infertility agents, and lactation-related toxins. The document emphasizes the lack of a definitive list for human reproductive toxins and provides guidelines for employee notification, personal protective equipment, hygiene practices, work area identification, handling and storage procedures, and waste disposal related to these hazardous substances.
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Category 1: Chemicals that have produced significant toxicity in humans, or that on the basis of evidence from studies in animals can be presumed to have the potential to produce significant toxicity in humans (emphasis in original) following repeated exposure.
Reproductive toxicity refers to the potential risk from a given chemical, physical or biologic agent to adversely affect both male and female fertility as well as offspring development.
There are three categories for reproductive toxins, Category 1A, 1B and 2, that you may see on safety data sheets (SDS) or on a chemical bottle.
A reproductive toxin is a substance or agent that can cause adverse effects on the reproductive system. The toxic effects may include alterations to the reproductive organs and/or to the endocrine system (which includes the thyroid and adrenal glands). These effects can occur in both men and women.
CATEGORY 1B: PRESUMED: PRESUMED to produce an adverse effect on reproductive ability or capacity or on development in humans. The placing of the substance in this category is largely based on evidence from experimental animals.

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Substances are classified in Category 1 for reproductive toxicity when they are known to have produced an adverse effect on sexual function and fertility, or on development in humans or when there is evidence from animal studies, possibly supplemented with other information, to provide a strong presumption that the
Category 1A: Known human reproductive toxicant Largely based on evidence from humans. Known to have produced an adverse effect on sexual function and fertility, or on development in humans. Category 1B: Presumed human reproductive toxicant Largely based on data from animal studies.
Reproductive hazards are substances or agents that may affect the reproductive health of women or men or the ability of couples to have healthy children. Hazards may be chemical, physical or biological. Examples of reproductive hazards are lead (chemical), radiation (physical) and certain viruses (biological).

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Chemical Hazards

Similarly, the term hazardous chemical refers to any chemical carcinogens, toxic or highly toxic agents, reproductive toxins Mount Holyoke College (MHC)

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