HLA Test Results - University of Virginia - virginia 2025

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A negative result means you dont have HLA-B27 in your blood. A positive result means HLA-B27 was found in your blood. You may have a higher-than-average risk of certain autoimmune diseases, such as ankylosing spondylitis and reactive arthritis.
How does HLA typing and matching happen? The first step is to have your blood drawn or the inside of your cheek swabbed. Your doctor will send the blood sample or cheek swab to lab where its tested to figure out your HLA type.
A foreign substance that stimulates the immune system to produce antibodies against it. on the surface of cells and tissues. It is used to match a transplant recipient (person receiving a transplant) with a compatible donor (person who gives their cells for a transplant).
This test looks for HLA-B27, which are proteins called antigens. These are found on the surface of white blood cells that are fighting infection. If you have HLA-B27, you may have an autoimmune disease. An autoimmune disease is when your immune system attacks your own cells.
To determine your HLA type, we need to test a sample of your blood. We then compare your test results to HLA type of the person who needs the cells to see if you match. This can take up to 10 business days to complete.
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HLA antibodies are commonly formed in women during pregnancy, after receiving a blood transfusion or organ transplant. HLA antibodies pose absolutely no risk to you. However, HLA antibodies in donated plasma or plasma blood products may be dangerous to transfusion recipients.

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