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BCR-ABL RNA PCR Quantitation for Leukemia - ohsu

BCR-ABL RNA PCR Quantitation for Leukemia - ohsu 2025

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The document provides detailed information about the BCR-ABL RNA PCR quantitation test for monitoring chronic myeloid leukemia (CML) at Knight Diagnostic Laboratories. It includes laboratory and correspondence addresses, contact information, test codes, clinical utility, methodology, specimen requirements, and references. The test is crucial for assessing minimal residual disease in patients undergoing tyrosine kinase inhibitor therapy and aims to achieve a major molecular response.

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What is the PCR test for BCR-ABL1 quantification?

The BCR-ABL1 Gene Rearrangement, Quantitative PCR test can measure the 2 P210 transcripts (e13a2 and e14a2) as well as the P190 transcript (e1a2). For P210 transcripts, results are standardized to the international scale (IS), allowing direct comparison across different laboratories regardless of method variations.

How much does BCR-ABL PCR quantitative test cost?

BCR-ABL Quantitative PCR (IS Scale) test price for other cities Price inNew DelhiRs. 6119 Price in Bangalore Rs. 6529 Price in Mumbai Rs. 6299 Price in Hyderabad Rs. 6179 Price in Kolkata Rs. 5669

What is the labcorp test code for BCR-ABL quantitative PCR?

480481: BCR/ABL - t(9;22) by RT-PCR (Quantitative) | Labcorp Oncology.

What is a PCR test for CML?

Polymerase chain reaction (PCR) It can be done on blood or bone marrow samples and can detect very small amounts of BCR-ABL, even when doctors cant find the Philadelphia chromosome in bone marrow cells with cytogenetic testing. PCR can be used to help diagnose CML.

What is BCR-ABL PCR quantitative?

The quantitative BCR-ABL RNA assay is intended to monitor the level of minimal residual disease in TKI-treated Philadelphia chromosome positive leukemias (CML or ALL). High or rising BCR-ABL RNA levels have been shown to increase the risk of leukemic relapse and drug-resistance mutations during TKI therapy.

What is the BCR-ABL test for leukemia?

A BCR-ABL1 genetic test uses a sample of blood or bone marrow to look for an abnormal gene called BCR-ABL1. This abnormal gene is involved in certain types of blood cancer. Its found in: Most people who have chronic myeloid leukemia (CML), which is also called chronic granulocytic leukemia or chronic myeloid leukemia.

What is the normal range for BCR-ABL quantitative PCR?

The normal range for the BCR-ABL test is 0-0.1%. A result that is above the normal range may be a sign of CML. The test is usually done as part of a complete blood count (CBC) and will be ordered by a doctor if they suspect that a person has CML.

BCR-ABL RNA PCR Quantitation for Leukemia - ohsu 2025

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