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ATTRACT Digital Site Application (PDF) - The ATTRACT Study

ATTRACT Digital Site Application (PDF) - The ATTRACT Study 2025

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The document is an application for participation in the NIH-sponsored ATTRACT Trial, which focuses on the treatment of deep vein thrombosis (DVT). It outlines the requirements for potential study sites, emphasizing the importance of site commitment, personnel qualifications, and effective patient identification mechanisms. The application includes sections for key personnel information, financial contacts, hospital details, research coordinator qualifications, oversight of anticoagulant therapy, endovascular resources, and a site-specific enrollment plan. The document stresses the need for thorough preparation and collaboration to ensure successful participation in this significant clinical trial.

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What is the attract study for DVT?

The ATTRACT Study was a large clinical trial that compared two commonly-used DVT treatment strategies (blood-thinning medications alone or blood-thinning medication plus catheter-directed clot removal) to determine which is best.

What is an attract trial?

ATTRACT is the first multicenter randomized controlled trial to assess pharmacomechanical catheter-directed thrombolysis (PCDT), an innovative, image-guided therapy.

What is the open vein hypothesis?

The open vein hypothesis posits that removing this obstruction through pharmacomechanical means may prevent PTS. This hypothesis has been tested in 2 large randomized controlled trials to date.

What is the conclusion of deep vein thrombosis?

CONCLUSION: Deep Venous Thrombosis is a common disease with fatal and serious long term burdensome complications.

What were the results of the clear DVT study?

There was no PTS in 96% of patients and mild PTS in the remaining 4%, with no Villalta score greater than five, Silver pointed out. The speaker concluded that the CLEAR-DVT study showed that contemporary venous intervention resulted in an open vein, which reduced PTS.

What is the conclusion of the attract trial?

What did ATTRACT find? Dr. Comerota: We found that 48% of our patients developed PTS by 2 years, and 24% of the patients developed moderate-to-severe PTS. However, the results indicated that in most patients with acute DVT, the additional PCDT did not reduce the overall occurrence of PTS.

What are the limitations of the attract trial?

Limitations of the trial included substantial missing assessments of post-thrombotic syndrome. The occasional missed visits were balanced between treatment groups, however among 80 patients with no post-thrombotic assessments, two thirds were in the control group.

ATTRACT Digital Site Application (PDF) - The ATTRACT Study 2025

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