Blood transfusion errors - RocketCare 2025

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Our analyses indicated that the failure risks with the highest RPNs were blood sample labelling (RPN 100), incorrect order for blood or the component transfusion (RPN: 100), error in patient identification (RPN: 80), and sampling (RPN: 75).
Risks and Complications Allergic Reactions. Some people have allergic reactions to blood received during a transfusion, even when given the right blood type. Fever. Developing a fever after a transfusion is not serious. Acute Immune Hemolytic Reaction.
Transfusion target is the Hb one aims to achieve after RBC transfusion. Traditionally, the rule of 10/30 was followed for RBC transfusion, ing to which a Hb level of 10 g/dl or a haematocrit of 30% was recommended in surgical patients.
The most frequent error leading to transfusion of ABO-incompatible blood occurs during patient identification/verification at the bedside; as a result, although the blood is labeled appropriately, it is transfused to someone other than the correct recipient.
The most common signs and symptoms include fever, chills, urticaria, and itching. Some symptoms may resolve with little or no treatment. However, respiratory distress, high fever, hypotension, and hemoglobinuria may indicate a more serious reaction.
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The risks of blood transfusions include: An allergic reaction. This can be mild or severe. Fever. Destruction of red blood cells by the body (hemolytic reaction). Too much blood in the body (transfusion overload). Too much iron in the body (iron overload). Viruses being transmitted. Graft-versus-host disease.
The most common cause of an acute intravascular hemolytic transfusion reaction is ABO incompatibility. The ABO blood group antigens are densely expressed on the RBC surface, and most people have adequate amounts of preformed antibodies that can not only bind to the RBCs but can also activate complement.