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Why is there a warfarin shortage?

Viatris Pty Ltd has advised the Therapeutic Goods Administration (TGA) of shortages of several warfarin products due to manufacturing issues.

Why is warfarin not used as much anymore?

Warfarin is most commonly discontinued because of physician preference, patient refusal, and bleeding events.

Why is warfarin being discontinued?

This action is voluntary and is not the result of any quality, safety or efficacy issues regarding the product, but rather due to an unexpected manufacturing issue that cannot be resolved. The discontinuation of this product in the U.S.A. happened on April 24th, 2020.

What is the controversy with warfarin?

The main adverse effect associated with warfarin is bleeding. Major and fatal bleeding events occur respectively at rates of 7.2 and 1.3 per 100 patient-years, ing to a meta-analysis of 33 studies [5].

Is there a better blood thinner than warfarin?

For example, warfarin requires frequent monitoring. And youll need to pay close attention to your diet during treatment, too. In this case, DOACs like Eliquis or Xarelto may be a better fit for your lifestyle.

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Why is warfarin not recommended?

Warfarin (Jantoven) is a medicine to prevent blood clots. It may save your life if youve had blood clots or are at risk of them. But warfarin can sometimes cause serious side effects, such as heavy bleeding. Its important to have regular health checkups if you take the medicine.

Which is better warfarin or new oral anticoagulants?

DOACs have been shown to be as effective at preventing strokes as warfarin. The main difference between DOACs and warfarin is that DOACs are less influenced by diet and other medications. A set dose of a DOAC can be prescribed and the doctor will know that you are protected against stroke as long as the drug is taken.

Which is better direct oral anticoagulants or warfarin?

In general, the DOACs are safer and more effective than warfarin, especially when it comes to serious bleeding. DOACs cause half as much life-threatening bleeding than warfarin. Theyre also more convenient than warfarin because they dont require frequent blood monitoring and can be given safely in fixed doses.

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