Principles of General and Autonomic Pharmacology Notices 2025

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Changes in the diameter of the pupils, dilation and constriction of blood vessels and adjustment of the rate and force of the heartbeat are examples of autonomic motor responses. increases heart rate and an increase in nerve impulses from the parasympathetic division decreases heart rate.
Peristalsis of the intestines is the example of the action of the autonomous nervous system. The organs of our body (viscera), the heart, intestines and stomach, are regulated by a branch of the nervous system known as the autonomic nervous system.
Table 1. Sympathetic and Parasympathetic Effects of Different Drug Types Drug typeExample(s) Nicotinic agonists Nicotene Sympathomimetic drugs Phenylephrine Sympatholytic drugs B-blockers such as propanolol or metaprolol; a-blockers such as clondine
Autonomic pharmacology is the study of how drugs interact with the autonomic nervous system. The autonomic nervous system plays an important role in the control of the internal organs including the heart, lungs, gastrointestinal tract and vasculature.
Autonomic pharmacology centers on the physiology of the sympathetic (SNS) and the parasympathetic (PSNS) nervous systems, regulating involuntary reactions to stress across multiple organ systems.
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Autonomic drugs are substances that can either inhibit or enhance the functions of the parasympathetic and sympathetic nervous systems. This type of drug can be used to treat a wide range of diseases an disorders, including glaucoma, asthma, and disorders of the urinary, gastrointestinal and circulatory systems.
The automatic nervous system has two antagonistic branches, the sympathetic and parasympathetic systems. Antagonistic, in this case, means that they have opposite functions. An example is how the sympathetic nervous system increases the heartbeat, and the parasympathetic nervous system slows it down.
Summary. The sympathetic and parasympathetic divisions of the autonomic nervous system innervate most ocular tissues. Important ocular functions, including pupil size, accommodation, ocular blood flow, and intraocular pressure, respond to regulation by the autonomic nervous system (Table 2.7).

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