Treating Tobacco Use and Dependence: A Quick Reference Guide - healthquality va 2025

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Bupropion and varenicline are medicines which work in a different way from nicotine replacement. The new medicines reduce cravings for nicotine without supplying a nicotine substitute, thereby supporting people in quitting tobacco use and reducing nicotine dependence.
Besides Chantix and Wellbutrin, nicotine replacement therapy (NRT) products are other options to help you quit smoking. The following NRT products are available: Nicotine patch (Nicoderm CQ) Nicotine lozenges and gum (Nicorette)
Use the 4Ds to tide over cravings: distract, delay, deep breathing, and drinking water.
WHO recommends varenicline, Nicotine Replacement Therapy (NRT), bupropion, and cytisine as effective treatments for tobacco cessation. In 2023, WHO initiated a prequalification procedure for medicinal products against disorders caused by tobacco use to improve global access to recommended tobacco cessation medications.
The clinician can motivate patients to consider a quit attempt with the 5 Rs: Relevance, Risks, Rewards, Roadblocks, and Repetition.
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Varenicline, formerly produced as Chantix, is the most effective single product to help you quit smoking. Varenicline is a medication taken in pill-form. It cuts cravings by acting like nicotine on the brain without actually containing any.
Successful intervention begins with identifying users and appropriate interventions based upon the patients willingness to quit. The five major steps to intervention are the 5 As: Ask, Advise, Assess, Assist, and Arrange. Ask - Identify and document tobacco use status for every patient at every visit.
Cytisinicline (historically known as cytisine) is a naturally occurring plant-based alkaloid that binds selectively to nicotinic receptors in the brain that regulate nicotine dependence, alleviating the urge to smoke and reducing the severity of nicotine withdrawal symptoms.

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