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What is Russell and Burchs replacement concept?

Authors Russell and Burch define a replacement technique as any scientific method employing non-sentient material which may in the history of experimentation replace methods which use conscious living vertebrates. Scientists should seek to replace animals in experiments with alternatives whenever possible.

What are the 3 Rs in animal testing?

The 3 Rs stand for Replacement, Reduction and Refinement. Replacement alternatives refer to methods which avoid or replace the use of animals.

When did animal testing start?

Animals have been used repeatedly throughout the history of biomedical research. Early Greek physician-scientists, such as Aristotle, (384 322 BC) and Erasistratus, (304 258 BC), performed experiments on living animals.

What is the 3r principle of animal experimentation?

What are the 3Rs ? The principle of reducing waste, reusing and recycling resources and products is often called the 3Rs. Reducing means choosing to use things with care to reduce the amount of waste generated. Reusing involves the repeated use of items or parts of items which still have usable aspects.

Why are animal experiments met with controversy?

Reliance On Animal Experimentation Can Impede and Delay Discovery. Drugs and procedures that could be effective in humans may never be developed because they fail in animal studies. It is difficult to know how frequently this occurs, since drugs that fail in animals are rarely tested in humans.

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