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Topiramate is FDA-approved for various types of epilepsy, migraine, and Lennox-Gastaut syndrome; however, it has numerous off-label uses and a docHub adverse drug reaction profile.
Topamax Lawsuits. Lawsuits blame Janssen Pharmaceuticals Inc. for birth defects in babies born to women who took Topamax while pregnant. Claims include Janssens failure to warn women and their doctors about the drugs risks.
Titration should begin at 25 mg/day (or less, based on a range of 1 to 3 mg/kg/day) nightly for the first week. The dosage should then be increased at 1- or 2-week intervals by increments of 1 to 3 mg/kg/day (administered in two divided doses), to achieve optimal clinical response.
Topamax comes in two forms: an oral tablet and a capsule filled with sprinkles of the active drug. The sprinkle capsule can be swallowed whole. Or it can be opened and sprinkled onto a teaspoon of soft food and then swallowed.
Collection Instructions: Draw blood immediately before next scheduled dose.
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Topamax Illegal Marketing In April 2010, Topamax manufacturers agreed to pay more than $81 million for illegal marketing of Topamax as part of a settlement with the U.S. Department of Justice. Manufacturers admitted to marketing the drug for unapproved psychiatric uses under a program called Doctor-for-a-Day.
Initiate topiramate at 25mg at night and slowly titrate upwards by 25mg per week as tolerated until an effective dose is docHubed. This can take 4-6 weeks, but longer intervals between dose adjustments may be needed if side effects, such as drowsiness, are troublesome.
The bottom line Topiramate is a medication prescribed for seizures and migraines. Mild side effects include a pins and needles sensation, weight loss, and drowsiness. Serious topiramate side effects include eye problems, metabolic acidosis, and suicidal thoughts. Severe issues may need immediate medical attention.
Topamax is a brand-name prescription medication thats FDA-approved in certain situations to: Prevent migraine headaches in adults as well as children ages 12 years and older. Treat epilepsy* in adults as well as children ages 2 years and older with: partial-onset seizures.

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