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In June 2013 the Japanese Ministry of Health, Labor, and Welfare (MHLW) suspended its HPV vaccination recommendation after a series of highly publicized alleged adverse events following immunization stoked public doubts about the vaccines safety.
Three HPV vaccines9-valent HPV vaccine (Gardasil 9, 9vHPV), quadrivalent HPV vaccine (Gardasil, 4vHPV), and bivalent HPV vaccine (Cervarix, 2vHPV)have been licensed by the U.S. Food and Drug Administration (FDA). All three HPV vaccines protect against HPV types 16 and 18 that cause most HPV cancers. HPV Vaccination: What Everyone Should Know | CDC cdc.gov vaccines vpd hpv public cdc.gov vaccines vpd hpv public
The FDAs approval of Cervarix was based on data from clinical trials in more than 30 countries involving a diverse population of nearly 30,000 girls and young women receiving Cervarix. FDA approves Cervarix, GlaxoSmithKlines cervical cancer gsk.com en-gb media press-releases f gsk.com en-gb media press-releases f
The most common side effects with Cervarix (seen in more than 1 patient in 10) are headache, myalgia (muscle pain), reactions at the site of injection including pain, redness and swelling, and fatigue (tiredness).
Both vaccines protect against infection with HPV-16 and HPV-18, the 2 serotypes that cause the majority of HPV-associated cancers. In addition, Gardasil protects against HPV-6 and -11, the most common causative agents of genital warts.
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The HPV vaccine used routinely in the national programme when the programme started in 2008 was Cervarix, which protects against HPV types 16 and 18. HPV Vaccine Coverage in England 2008/9 to 2013/14 - GOV.UK service.gov.uk media HPV service.gov.uk media HPV
The vaccine used in the trial, known as Cervarix, is no longer available in the United States, but it is still used in some countries. It is one of three World Health Organizationrecommended HPV vaccines that protect against sexually transmitted infections with disease-causing HPV types.
An alternative product, from Merck Co., is known as Gardasil. Cervarix was voluntarily taken off of the market in the US in 2016 due to low demand. Cervarix - Wikipedia wikipedia.org wiki Cervarix wikipedia.org wiki Cervarix

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