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Standard Operating Procedures (SOP) are required prior to working with or near any chemical designated as highly hazardous. Some SOPs may require review and approval by Research Safety Committees prior to project approvals or the issuance of an Animal Use Safety Information (AUSI) Sheet.
Before beginning work with acutely toxic chemicals, all personnel must have completed the following: Laboratory Safety for Researchers. Read the relevant Safety Data Sheets (SDSs). Complete any laboratory-specific training necessary to perform the procedures listed in this SOP. Read and sign this SOP.
5 Essentials for Every SOP Keep a Clear User Viewpoint. You should always be thinking about your end user when you write an SOP. Format Clearly. As well as being careful with language, process documentation should always use intuitive formatting. Keep Scope in Mind. Observe Roles and Impacts. Seek Authority and Approval.
How to write an SOP: A step-by-step guide Step 1: Identify the Process. Step 2: Gather a Team. Step 3: Define Scope and Objectives. Step 4: Break Down the Process. Step 5: Assign Roles and Responsibilities. Step 6: Review and Test. Step 7: Implement and Train. Step 8: Monitor and Revise.
A Standard Operating Procedure (SOP) describes how your lab will safely handle a hazardous chemical, including the amount and concentration you will use, how you obtain or create the working solution, and special handling procedures, engineering controls, and personal protective equipment.
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A standard operating procedure (SOP) provides clear-cut directions and detailed instructions needed to perform a specific task or operation consistently and efficiently. Often seen in a myriad of industries, SOPs aim to achieve uniformity in execution, reduce miscommunication, and adhere to regulatory standards.
SOPs are written instructions that detail the steps to be performed during a given experimental procedure and include information about potential hazards and how these hazards will be mitigated. SOPs should be written by laboratory personnel who are most knowledgeable and involved with the experimental process.
An SOP should include a clear title that names the procedure, why this SOP was created, and step-by-step instructions that include who is responsible for each step. Any quality standards or turnaround timelines should be specified.

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