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Bosentan is used to treat pulmonary arterial hypertension (PAH, high blood pressure in the vessels that carry blood to the lungs) in adults and children 3 years of age and older. Bosentan may improve the ability to exercise and slow the worsening of symptoms in patients with PAH. Bosentan: MedlinePlus Drug Information medlineplus.gov druginfo meds medlineplus.gov druginfo meds
Descriptions. Bosentan is used to treat the symptoms of pulmonary arterial hypertension (PAH) in adults or in children 3 years of age or older. It improves the ability to exercise and slows down the worsening of the patients physical condition.
Bosentan Clinical data Trade names Tracleer, Stayveer, Safebo AHFS/Drugs.com Monograph MedlinePlus a605001 License data US DailyMed: Bosentan31 more rows
Bosentas 125 Tablet is a prescription medicine used to treat pulmonary arterial hypertension (high pressure in the blood vessels that carry blood from the heart to the lungs). It even helps to improve your quality of life, exercising ability and delay in disease progression.
The mechanism of action of bosentan is competitive inhibition of endothelin-1 receptors. Endothelin-1 is a potent vasoconstrictor, which also mediates cell proliferation, fibrosis and inflammation. It is mainly synthesized in endothelial cells and acts locally in autocrine and paracrine fashion. Bosentan in the treatment of pulmonary arterial hypertension nih.gov articles PMC2725793 nih.gov articles PMC2725793
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Macitentan is used to manage the symptoms of pulmonary arterial hypertension (PAH; high blood pressure in the vessels that carry blood to the lungs). Macitentan: MedlinePlus Drug Information medlineplus.gov druginfo meds medlineplus.gov druginfo meds
This medication blocks the effects of endothelin-1, which helps lower blood pressure in the lungs, slow the worsening of symptoms from the disease, and improve your ability to exercise.

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