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The general formula of QAC is N + R 1 R 2 R 3 R 4 X , where R can be a hydrogen atom, a plain alkyl group or an alkyl group substituted with other functional groups, and X represents an anion; see Figure 1.
Three types of QACs used as antimicrobials have been reported to cause irritant and/or allergic contact dermatitis [2, 3, 11, 12, 13]. These QACs are the benzalkonium chlorides, didecyl dimethyl ammonium chloride (DDAC), and N,N-didecyl-N-methyl-poly(oxyethyl) ammonium propio- nate.
Applications. Quaternary ammonium salts are used as disinfectants, surfactants, fabric softeners, and as antistatic agents (e.g. in shampoos). In liquid fabric softeners, the chloride salts are often used.
What are quaternary ammonium compounds (QACs/Quats)? Quats are a group of chemicals used for a variety of purposes, including as preservatives, surfactants, antistatic agents and as active ingredients for disinfectants and sanitizers.
Quaternary Ammonium Compounds, act by disrupting membranes. Quats are bactericidal (a drug or substance which kills bacteria, or is capable of killing bacteria) against Gram-positive bacteria and are less active against Gram-negative bacteria. They are fungicidal and virucidal.

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Quaternary ammonium compounds, also called quats or QACs, are a group of chemicals used for a variety of purposes including as preservatives, surfactants, antistatic agents, and as active ingredients in disinfectants and sanitizers.
Quaternary ammonium compounds (QACs), a large class of chemicals that includes high production volume substances, have been used for decades as antimicrobials, preservatives, and antistatic agents and for other functions in cleaning, disinfecting, personal care products, and durable consumer goods.
Quaternary Ammonium Compounds (QACs) are a type of chemical that is used to kill bacteria, viruses, and mold. There are many different types of QACs. They are often found in dis- infectants and in cleaning products that are used in places such as hospitals, day care centers, restaurants, and homes.

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