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Is buprenorphine a treatment for major depression and opioid use disorder?

Buprenorphine, a mixed opioid receptor agonist/antagonist approved for the treatment of OUD and chronic pain, may have potential as a novel therapeutic for MDD, especially for patients with a dual diagnosis of MDD and OUD.

Why would a doctor prescribe buprenorphine?

What is buprenorphine used for? Buprenorphine is prescribed for the medical treatment of people with an opioid drug dependence. This could include a dependency on heroin or other opioid medicines. Buprenorphine can help people safely withdraw from the opioid medicine they are dependent on.

What is the major advantage of buprenorphine?

The main advantages of buprenorphine are: You are unlikely to overdose on buprenorphine if you take it properly. Buprenorphine is long acting. This means that after an initial period, your doctor may have you take the pill every other day rather than once a day.

Why is buprenorphine addictive?

Buprenorphine is a synthetic opiate and produces the euphoric effects sought by opiate abusers; there- fore, it is susceptible to abuse in both of the forms approved for treating opiate addiction.

Is buprenorphine better than abstinence?

The results determined that medications for OUD docHubly reduced the risk of death by 38% for methadone and 34% for buprenorphine. People who received treatment that did not utilize medications (abstinence-based therapy) were 1.2 to 1.7 times more likely to die than those who were exposed to no treatment at all.

Why is buprenorphine preferred?

Buprenorphine has unique pharmacological properties that help: Diminish the effects of physical dependency to opioids, such as withdrawal symptoms and cravings. Increase safety in cases of overdose. Lower the potential for misuse.

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