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Desmopressin acetate is the preferred medication for treating children with enuresis. A Cochrane review of 47 randomized trials concluded that desmopressin therapy reduces bedwetting; children treated with desmopressin had an average of 1.3 fewer wet nights per week.
Explanation and reassurance, and rewards. ➢ Bedwetting is not the childs fault. Advice on diet and fluid intake. ➢ Eat a healthy diet and ensure an adequate daily fluid intake (see table below) Toileting and lifting and waking advice. ➢ Empty bladder regularly during day and before sleep (4-7 x a day) Nocturnal enuresis (bed wetting) - BSUH Paediatric Guidelines University Hospitals Sussex NHS Foundation Trust sites 2020/06 Pae University Hospitals Sussex NHS Foundation Trust sites 2020/06 Pae PDF
General advice Emphasise that bedwetting is not the childs fault. Explain the importance of adequate fluid intake and advise both the child and parents/carers not to restrict fluid or diet as a treatment for bedwetting. Encourage children to use the toilet regularly (47 times per day is considered normal).
Definitions of nocturnal enuresis have traditionally used 5 years as a cut off point. From a developmental perspective children are expected to be dry at night at 5 years of age.
This usually happens between 4 and 6 years of age. A healthcare provider will see bedwetting as an issue if your child is over age 12 and continues to wet the bed two or more times a week for at least three months in a row. Although bedwetting isnt a serious condition, it can cause stress for your child and family.

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First-line treatment for monosymptomatic nocturnal enuresis Nocturnal polyuria can be treated using the vasopressin analogue desmopressin, which reduces the amount of urine during the night. In most countries the recommended starting dose for children is 120 g/day (melt) or 200 mg/day (tablet). Enuresis: practical guidelines for primary care - PMC - NCBI National Institutes of Health (NIH) (.gov) articles PMC5565868 National Institutes of Health (NIH) (.gov) articles PMC5565868
DSM-5 criteria for enuresis are as follows: Repeated voiding of urine into bed or clothes, whether involuntary or intentional. The behavior either (a) occurs at least twice a week for at least 3 consecutive months or (b) results in clinically docHub distress or social, functional, or academic impairment. Enuresis: Practice Essentials, Background, Pathophysiology medscape.com 1014762-overview medscape.com 1014762-overview
Definitions of nocturnal enuresis have traditionally used 5 years as a cut off point. From a developmental perspective children are expected to be dry at night at 5 years of age. Under 5 year olds and management of bedwetting - Nocturnal Enuresis nih.gov books NBK62723 nih.gov books NBK62723

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