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To prescribe, administer, or authorize for administration a Schedule III, IV, or V controlled substance in Alabama, Certified Registered Nurse Practitioners (CRNP) and Certified Nurse Midwives (CNM) must obtain annually a Qualified Alabama Controlled Substances Certificate (QACSC).
Yes. The rules governing Collaborative Practice in AL do not prohibit a CRNP or CNM from owning a practice. However, CRNPs and CNMs who desire to practice are required to enter into a Collaborative Practice Agreement with a physician licensed in the state of Alabama.
Some U.S. jurisdictions, including Alabama (ABME Admin. Code, 2022; ABN Admin. Code, 2021a, 2021b; Code of Ala. 1975, 2002, 34-21), prohibit the independent practice of APRNs, who are educationally and experientially prepared to practice independently.
Section 540-X-8-. 12 - Limitations Upon Utilization Of Certified Registered Nurse Practitioners (1) A physician may enter into collaborative agreements with certified registered nurse practitioners not exceeding a cumulative three hundred and sixty (360) hours (nine FTEs) per week.
Certified nurse practitioners and PAs can write prescriptions for C-II controlled substances if the following requirements have been met: Must be registered with the Board of Medical Examiners with a DEA # and have the practice registration amended to include C-IIs. Must have a current collaborative practice agreement.

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The collaborative practice agreement specifies the duties to be performed, how documentation and communication between practitioners will be handled, plans for quality assurance, and other details. A standard protocol and formulary outline the typical care and services that would be provided.
An unencumbered license as a Registered Nurse in Alabama or a VALID MSL-RN from a compact state is required for initial approval as an advanced practice nurse. None. Masters or higher degree in nursing from an educational institution in a curriculum designed to prepare nurse practitioners.
PAs are educated in general medicine, which offers a comprehensive view of all aspects of medicine. NPs must choose a population focus, e.g., pediatric nurse practitioner or womens health nurse practitioner. PAs are trained to practice medicine using a curriculum modeled on medical school education.

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