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Muscle Biopsy Handling Instructions - chop 2025

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The document provides detailed instructions for handling and processing muscle biopsies at the Children's Hospital of Philadelphia. It outlines the requisition process, specimen preparation guidelines, freezing methods, and transportation protocols to ensure accurate evaluation of various neuromuscular disorders. Key contacts and shipping addresses are also included.

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Can you shower after a muscle biopsy?

Take a sponge bath so you dont get your cut wet, unless told otherwise. Ask the healthcare provider when you can take a shower or bath. Ask the best way to keep your cut dry when bathing or showering. You may have a small rim of redness and swelling around the cut.

How to transport a muscle biopsy?

Wet tissue: Double bag the specimen container with the requisition on the outside of the plastic bag. Placed the double-bagged specimen into a Styrofoam box (primary container) with adequate wet ice to keep specimen cool during transport. Securely seal the primary container.

What to do after a muscle biopsy?

What happens after a muscle biopsy? Once you are home, its important to keep the biopsy area clean and dry. Your healthcare provider will give you specific bathing instructions. If you have stitches, your healthcare provider will remove them during a follow-up office visit.

What is the aftercare for a muscle biopsy?

You may resume your usual diet and activities, unless your healthcare provider advises you otherwise. Your healthcare provider may restrict your activity for 24 hours following the procedure and ask that you avoid excessive use of the biopsied muscle.

Can you walk after a muscle biopsy in your leg?

An open biopsy wound may be closed with stitches. The surgeon will advise when these can be removed and who will do this. On the day of the biopsy, walking is possible but should be minimised. Activity should gradually be resumed following the procedure.

What should you not do after a biopsy?

For 3 days after your biopsy, do not: Lift anything heavier than 5 pounds (2.3 kilograms). Do any strenuous exercises, such as running or jogging. Bathe, swim, or soak the biopsy site under water. You may shower 24 hours after your biopsy.

What are the requirements for a muscle biopsy?

Collection requirements and precautions The biopsy should be approximately 1.5 cm x 0.5 cm and dissected with minimal trauma along the long axis of the muscle fibers. If extra studies are needed, then another piece of similar size should be obtained. Do not use electrocautery or a muscle clamp in removing the specimen.