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What are the saliva diagnostic markers?

Many of the enzymes have been utilized as diagnostic markers. Approaches based on salivary enzymatic methodologies are widely used for the diagnosis of diseases, including cardiovascular diseases,144 Alzheimers disease,145 oral diseases,146,147 and cancer. Two major focuses of salivary enzymes were pepsin and amylase.

What diseases can be diagnosed by testing saliva?

Saliva has been reliably used to detect HIV-1 and -2, and viral hepatitis A, B and C. It can also be used to monitor a variety of drugs including marijuana, cocaine and alcohol (1). There are compelling reasons to use saliva as a diagnostic fluid to monitor health and diseases.

What information can be obtained from saliva?

Human saliva can be easily obtained by noninvasive techniques and contains many analytes of interest for screening, diagnosis and monitoring. These include steroid and other nonpeptide hormones, therapeutic drugs, drugs of abuse and antibodies.

What tests can be done with saliva?

Since noncomplexed hormones may be assayed readily in oral fluid samples, saliva has become a popular choice for testing the levels of cortisol, testosterone, DHEA, progesterone and many other hormones using standard laboratory ELISAs [8].

What hormones can be detected in saliva?

Published research has substantiated the accuracy of saliva testing in determining the values of specific hormones such as the major estrogens (estradiol, estrone, estriol), progesterone, androgens (dehydroepiandrosterone, testerone, 5a-dihydrotestosterone), cortisol, and melatonin.

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