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Does your immune system know that your eyes exist?

The eye is one of a few areas of the body with immune privilege. The eye limits its inflammatory immune response so that vision isnt harmed by swelling and other tissue changes. Other sites with immune privilege include the brain, testes, placenta and fetus.

What is the acceptance rate for Iovs?

In contrast to the growing submission rate, the rate of acceptance has fallen from approximately 50% to close to 40% over the past 2 years. This reflects the careful work of the associate editors, editorial board members, and the many colleagues who review the articles submitted to IOVS.

What happens if your immune system finds your brain?

Immune activity in the brain can be highly detrimental, Rustenhoven said. It can kill neurons and cause swelling. The brain cant tolerate much swelling because the cranium is a fixed volume. So immune surveillance is pushed to the borders, where the cells can still monitor the brain but dont risk damaging it.

What parts of the body have immune privilege?

Sites with immune privilege are anatomical regions that are naturally less subject to immune responses than most other areas of the body. Immune-privileged sites include the central nervous system and brain, the eyes and the testes.

Is your brain aware of your eyes?

The brain recognizes what your eyes see and can interpret those visual information or stimulus, so you can understand what you are reading or seeing.

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