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Unfortunately, standards of diagnosis and data recording may change, and conclusions from time trends call for particular wariness. The data from which epidemiology seeks to draw conclusions are nearly always collected by more than one person, often from different countries.
Cannot measure incidence. Selection of appropriate controls to minimize bias can be complicated. Medication exposures are often too rare to evaluate.
Some of the problems with studies are discussed including the specification of the data collected, accuracy of information, end point definition, study size and the way results are presented.
These challenges include difficulties in planning for data collection in a fragmented healthcare system, standardizing data collection when resources are limited, working in communities with access restricted by the military, and considerations related to the study setting.
Epidemiology is the study of how often diseases occur in different groups of people and why. Epidemiological information is used to plan and evaluate strategies to prevent illness and as a guide to the management of patients in whom disease has already developed.
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Exposures of interest to social epidemiologists include individual-level measures (e.g., poverty, education, social isolation), contextual factors (e.g., residential segregation or income inequality), and social policies (e.g., policies creating income security or promoting educational access).
Social epidemiology impact As a result, the research conducted by social epidemiologists has the potential to guide the development of public policy and help the communities most impacted by the political and economic policy decisions that impact many of our lives.
Finally, perhaps the most important limitation of epidemiology is that epidemiology and the data gathered by epidemiologic methods are routinely ignored.

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