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For example, NIEHS scientists discovered women living in areas with higher levels of air pollution may have a higher risk of breast cancer. 3 Research that helps us figure out how to reduce contact with environmental factors linked to breast cancer presents tremendous opportunity for disease prevention.
Breast cancer mainly occurs in middle-aged and older women. The median age at the time of breast cancer diagnosis is 62. This means half of the women who developed breast cancer are 62 years of age or younger when they are diagnosed. A very small number of women diagnosed with breast cancer are younger than 45.
Many studies have shown that unilateral breast cancer is more frequent in the left breast than in the right. This has been investigated in the Icelandic Cancer Registry. Information on all but 18 female breast cancer cases diagnosed in the forty-year-period from 1948 to 1987, a total of 2139 cases, was used.
Breast cancer is caused when the DNA in breast cells mutate or change, disabling specific functions that control cell growth and division. In many cases, these mutated cells die or are attacked by the immune system. But some cells escape the immune system and grow unchecked, forming a tumor in the breast.
The risk for breast cancer increases with age. Most breast cancers are diagnosed after age 50. Genetic mutations. Women who have inherited changes (mutations) to certain genes, such as BRCA1 and BRCA2, are at higher risk of breast and ovarian cancer.
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The Program on Breast Cancer and Environmental Risk Factors (BCERF) at Cornell University is devoted to lowering the risk and incidence of cancer by promoting methods of sound decision-making at personal and public levels. What Are Environmental Risk Factors? Cancer is a complex disease.
increasing age. family history. inheritance of mutations in the genes BRCA2, BRCA1 (more common with Ashkenazi Jewish heritage) and CHEK2. exposure to female hormones (natural and administered)
Risk factors Being female. Women are much more likely than men are to develop breast cancer. Increasing age. A personal history of breast conditions. A personal history of breast cancer. A family history of breast cancer. Inherited genes that increase cancer risk. Radiation exposure. Obesity.

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