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The newest drug (approved September 28, 2021) for the prevention of migraine (episodic migraine) is Qulipta (atogepant).
Lasmiditan (Reyvow) is a novel 5-HT 1F receptor agonist and is used as abortive treatment for moderate to severe migraines.
Preventive medications, sometimes called prophylactic medications, are designed to stop migraine attacks from starting. CGRP monoclonal antibodies like erenumab (Aimovig), fremanezumab (Ajovy) and galcanezumab (Emgality) are the latest preventative drug therapies. You get them by self injection about every month.
The US Food and Drug Administration (FDA) has approved Zavegepant, the first nasal spray for fast-acting migraine relief. Zavegepant, which will be sold under the brand name Zavzpret, is the first and only calcitonin gene-related peptide (CGRP) receptor to be approved by the agency for migraine treatment.
Theories about migraine pain Older theories about migraines suggested that symptoms were possibly due to fluctuations in blood flow to the brain. Now many headache researchers realize that changes in blood flow and blood vessels dont initiate the pain, but may contribute to it.
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Official answer Migraine Treatment. The newest novel drug (approved March 9, 2023) for the treatment of migraine is Zavzpret (zavegepant) nasal spray. Migraine Prevention. The newest drug (approved September 28, 2021) for the prevention of migraine (episodic migraine) is Qulipta (atogepant).
In the new theory proposed by the present author, the primary cause of migraines is the activation of the cervical complex of the trigeminal nucleus and trigeminal nerve.
On March 10, 2023, Pfizers zavegepant (Zavzpret)the first and only calcitonin gene-related peptide (CGRP) receptor antagonist nasal spray for acute migraine treatment in adultswas approved by the FDA.

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