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Advantages include: QALYs show health benefits in terms of both quantity and quality of life. CUA facilitates comparisons across different health interventions and policies by using a common unit of effect ( QALY ) CUA can inform resource allocation decisions across different healthcare settings.
A further advantage of QALYs, is that they allow the effectiveness and cost-effectiveness (or cost-utility) of interventions applied in very different disease areas to be compared, even when, because of their different outcomes, they would not be comparable within a CEA [8].
Concerns include that QALYs are not patient focused,1 may be used as rationing tools by health insurers, and may be perceived as dehumanizing. The Affordable Care Act prohibits the Patient-Centered Outcomes Research Institute from using cost-per-QALY benchmarks.
Since the popularisation of QALYs, clinicians, researchers, and ethicists have identified a number of limitations with the metric relating to time factors, utility factors and algorithm variation. These limitations can be considered as ethical, methodological, and disease- specific or contextual in nature.
Concerns include that QALYs are not patient focused,1 may be used as rationing tools by health insurers, and may be perceived as dehumanizing. The Affordable Care Act prohibits the Patient-Centered Outcomes Research Institute from using cost-per-QALY benchmarks.
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The quality-adjusted life year (QALY) is the academic standard for measuring how well all different kinds of medical treatments lengthen and/or improve patients lives, and therefore the metric has served as a fundamental component of cost-effectiveness analyses in the US and around the world for more than 30 years.

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