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Interval breast cancer (IBC) is the cancer detected after a normal screening mammogram but before the next scheduled mammogram. Therefore, IBC by definition defies assumptions necessary for screening mammography to be maximally effective.
Women 45 to 54 should get mammograms every year. Women 55 and older can switch to a mammogram every other year, or they can choose to continue yearly mammograms. Screening should continue as long as a woman is in good health and is expected to live at least 10 more years.
Breast Cancer Screening Recommendations The USPSTF recommends that women who are 50 to 74 years old and are at average risk for breast cancer get a mammogram every two years. Women who are 40 to 49 years old should talk to their doctor or other health care provider about when to start and how often to get a mammogram.
An interval increase in the size of a tumor refers to the growth or enlargement of a tumor over a specific period of time. It is typically measured by comparing the size of the tumor in two consecutive imaging scans, such as CT scans or MRI scans. This increase in size can be an indication of cancer progression.
Interval cancers occur in around 3 of every 1,000 women screened.
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interval breast cancers are more likely to be high-grade (grade 3) and to have a more aggressive natural history. A recent retrospective Canadian study, published in JAMA Network Open, found that these women had a higher risk for aggressive disease and death.
The task force says reducing the age of initial screening to 40 could prevent at least one additional breast cancer death for every 1,000 women. This change now creates a more uniform recommendation among all medical societies urging all women to initiate screening at age 40.
The interval cancer rate in the Malm Breast Tomosynthesis Screening Trial (MBTST) was 1.6 per 1000 screened women (95% CI: 1.0, 2.4) compared with 2.8 per 1000 screened women (95% CI: 2.2, 3.6) in the control group. The age-adjusted odds ratio was 0.6 (95% CI: 0.3, 0.9; P = . 02).
In the Netherlands we have three cancer screening programs: breast screening, cervical screening and bowel cancer screening. Health screening is offered by the government. Participation is free and voluntary.
Breast screening: interval cancers explained An interval cancer is an invasive cancer diagnosed within the 3-year period after a normal result. Interval cancers occur in around 3 of every 1,000 women screened.

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