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What is the difference of HIV-1 and HIV 2?

HIV-1 and HIV-2 share many similarities including their basic gene arrangement, modes of transmission, intracellular replication pathways and clinical consequences: both result in AIDS. However, HIV-2 is characterised by lower transmissibility and reduced likelihood of progression to AIDS.

What is unique recombinant form HIV?

CRFs are recombinant HIV-1 genomes that share the same recombination breakpoints (BPs) between the same parentals and have been found in at least three non-epidemiologically related individuals. If a recombinant form does not fulfill the requirements to be considered a CRF, it is called a unique recombinant form (URF).

What are HIV circulating recombinant forms?

Circulating recombinant forms (CRFs) are strains that have been observed in at least three epidemiologically unlinked individuals, whereas unique recombinant forms (URFs) have been observed in two individuals.

What is unique recombinant forms?

CRFs are recombinant HIV-1 genomes that share the same recombination breakpoints (BPs) between the same parentals and have been found in at least three non-epidemiologically related individuals. If a recombinant form does not fulfill the requirements to be considered a CRF, it is called a unique recombinant form (URF).

What is HIV recombination?

Homologous recombination can occur when a cell is coinfected with two different but related strains. Naturally occurring recombinant HIV strains have been found in infected patients in regions of the world where multiple genotypic variants cocirculate.

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What is HIV recombination?

Homologous recombination can occur when a cell is coinfected with two different but related strains. Naturally occurring recombinant HIV strains have been found in infected patients in regions of the world where multiple genotypic variants cocirculate.

What is circulating recombinant form of HIV?

Circulating recombinant forms (CRFs) are strains that have been observed in at least three epidemiologically unlinked individuals, whereas unique recombinant forms (URFs) have been observed in two individuals.

What are the 4 types of HIV?

HIV-1 viruses can be further stratified into groups M, N, O, and P. Among these, HIV-1 group M viruses are the most prevalent, infecting nearly 90% of people living with HIV and are responsible for the global AIDS pandemic. Group M can be further subdivided into subtypes based on genetic sequence data.

What is the global distribution of HIV-1 subtypes?

HIV-1 accounts for 95% of infections globally and is divided into 4 groups (M, N, O, and P), with group M containing 9 distinct subtypes, or clades [4, 5], the main ones being C, B, and A, which make up around 70% of the global distribution of HIV-1 [6].

What are the subtypes of HIV?

Based on different genome sequences risen from an independent cross-species transmission event, we can distinguish HIV-1 groups M (major), O (outlier), N (non-M, non-O), and P. Group M is the most widespread and includes nine subtypes: A, B, C, D, F, G, H, J, and K.

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What is HIV recombination?

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