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Is MF59 safe?

In humans, MF59 is a safe and potent vaccine adjuvant that has been licensed in more than 20 countries (Fluad [Novartis Vaccines and Diagnostics Inc., MA, USA]). The safety profile of an MF59-adjuvanted vaccine is well established through a large safety database.

What is the function of MF59?

MF59 is composed of squalene droplets stabilized with small amounts of the surfactants Tween 80 and Span 8571, it can docHubly enhance the potency of influenza antigens and increase the breadth of the immune response by increasing the cross-reactivity of viral strains not included in the vaccine.

What are the side effects of MF59?

The most common adverse reaction is a flu-like syndrome, usually during the first administration; it can be managed by pretreatment with a non-steroidal anti-inflammatory drug or paracetamol [8,9]. Headache, nausea, and myalgias also occur [10].

Is there one vaccine available to address all forms of influenza?

Flu Shot Types All flu vaccines currently available are quadrivalent vaccines. This means that they provide protection against the four most common flu virus strains that are predicted to be circulatingtwo influenza A strains and two influenza B strains.

What strains are in the flu shot 2017?

2 March 2017 It is recommended that trivalent vaccines for use in the 2017-2018 northern hemisphere influenza season contain the following: an A/Michigan/45/2015 (H1N1)pdm09-like virus; an A/Hong Kong/4801/2014 (H3N2)-like virus; and. a B/Brisbane/60/2008-like virus.

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