Title Rabies Specimen Collection and Transport Short Name Rabies - in 2025

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Fresh tissue samples from the central nervous system (brain) should be submitted. Postmortem diagnosis of rabies is made by immunofluorescent staining of viral antigen in touch impressions of the medulla (brain stem), the cerebellum, and the hippocampus. Fresh, non-formalin-fixed tissues are preferred.
Rabies is also known as hydrophobia. Rabies is a viral disease that causes acute inflammation of the brain in humans and other warm-blooded animals. Hydrophobia fear of water is the historic name for rabies.
Clinical rabies in people can be managed but very rarely cured, and not without severe neurological deficits. There are two forms of rabies: Furious rabies results in hyperactivity, excitable behaviour, hallucinations, lack of coordination, hydrophobia (fear of water) and aerophobia (fear of drafts or of fresh air).
Rabies has also occasionally been referred to as hydrophobia (fear of water) throughout its history.
Rabies is a fatal, acute, progressive encephalomyelitis caused by neurotropic viruses in the family Rhabdoviridae, genus Lyssavirus.
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