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The numbers tell the story: ing to Food and Drug Administration data, in 2020 75% of trial participants were white, 11% were Hispanic, 8% were Black, and 6% were Asian.
Minority participation in clinical trials is affected by multiple factors. Multiple patient-level factors including distrust in doctors,7 low English proficiency,5 and organizational religiosity8 have been investigated as potential barriers to minority participation in cancer clinical trials.
While all the trials included data on patient gender, only about 40 percent included any data on patient race or ethnicity. Of that 40 percent, the vast majority of participants 94 percent were white. Only 2.1 percent were Black, and 0.6 percent were Hispanic.
Several factors that affect the participation of African Americans in studies have been identified17,18 including elements of study design,1921 logistical problems, low levels of health literacy, sociocultural factors, and specific attitudes that hinder research participation.
What is exclusion criteria? Exclusion criteria is a list of characteristics that disqualify a person from participating in a clinical trial. These characteristics can vary from demographic information like age, gender, or race to something as complex as comorbidities, organ dysfunction, or the use of other medications.
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One factor in lower participation of Black and Hispanic adults in clinical trials is tied to concerns about past mistreatment in medical research, such as the U.S. Public Health Service Syphilis Study at Tuskegee or instances of medical doctors who sterilized racial and ethnic minority women without their full
Several factors that affect the participation of African Americans in studies have been identified17,18 including elements of study design,1921 logistical problems, low levels of health literacy, sociocultural factors, and specific attitudes that hinder research participation.
Of the 612 articles, 486 (79.4%) reported participant race and 338 (55.2%) reported participant ethnicity. From 2011 to 2020, relative rates of reporting of participant race increased by 7.9% per year (95% CI, 0.2%-16.3% per year) and reporting of ethnicity increased by 11.4% per year (95% CI, 4.8%-18.4% per year).
NIH follows the Office of Management and Budget (OMB) standard and capitalizes all references to race equally. Avoid collective reference to racial and ethnic minority groups as non-White unless it was a formal category in a database or research document. Instead, indicate the specific groups.
H should be selected if a person chooses to identify himself as Hispanic or Latino. N should be selected if a person chooses to identify himself as an ethnicity other than Hispanic or Latino. Only one ethnicity choice is allowed, i.e., a person cannot select both H and N.

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