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Use of platelet transfusions prior to lumbar punctures or

Use of platelet transfusions prior to lumbar punctures or 2025

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The document outlines the procedure of intrathecal chemotherapy, which involves puncturing the lumbar spine to extract cerebrospinal fluid (CSF) for analysis and administer drugs directly into the CSF for treating or preventing central nervous system (CNS) diseases, particularly hematologic malignancies. It details the procedure's purpose, benefits, risks, alternatives, and consequences of not performing it. Common risks include headaches and temporary meningeal irritation, while infrequent but serious risks involve CNS infections and complications like intracranial hematoma. The document also includes a consent declaration for patients.

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Why would a patient need platelets?

Although most cardiac surgeons will offer a surgical option to a patient with moderate thrombocytopenia (platelet count around 70 10 9/L), successful cardiac surgery has not been reported in patients with significantly lower platelets counts (less than 40 10 9/L).

What is the platelet count before lumbar puncture?

As there is currently no consensus on the standard platelet count threshold prior to an LP or epidural anaesthesia, we compared the most commonly recommended platelet count threshold in national guidelines (50 x 109/L) against other recommended thresholds (10 x 109/L, 20 x 109/L, 30 x 109/L, 40 x 109/L, 80 x 109/L).

When should platelet transfusion be given?

Platelet transfusion is recommended when the platelet count falls below a certain threshold, either as a preventive measure before specific procedures or to prevent spontaneous bleeding.

What platelet count is needed for surgery?

However it is generally accepted that a count of 50,000/uL is sufficient for most invasive procedures including most surgeries. Platelet counts of 100,000/uL are recommended for ophthalmic and neurosurgery. Higher transfusion thresholds may be appropriate for patients with platelet dysfunction.

What should platelet count be before epidural?

Data cautiously extrapolated from alternative patient populations suggest that interlaminar epidural access with platelet counts of at least 70,000 are associated with low risk of epidural hematoma in the absence of coagulopathy and drugs that are capable of inducing platelet dysfunction.

What does platelet count indicate?

Platelets control bleeding in our bodies, so they can be essential to surviving surgeries such as organ transplant, as well as fighting cancer, chronic diseases, and traumatic injuries.

Why would you need platelets before surgery?

Platelets are tiny cells in the blood that form clots to help stop bleeding. If a person with a low platelet counts requires surgery they are at increased risk of bleeding during and after surgery.

Use of platelet transfusions prior to lumbar punctures or 2025

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