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Genetic tests can help show if members of certain families have inherited a high risk of colorectal cancer due to inherited cancer syndromes such as Lynch syndrome (also known as hereditary non-polyposis colorectal cancer, or HNPCC) or familial adenomatous polyposis (FAP).
Lynch syndrome (hereditary non-polyposis colon cancer or HNPCC) Lynch syndrome is the most common hereditary colorectal cancer syndrome. It accounts for about 2% to 4% of all colorectal cancers.
During genetic testing, we may take a sample of tissue from your blood, a polyp, or a tumor (if you already have colon cancer). Well look at the sample for changes in your genes that are associated with hereditary syndromes that cause colon cancer.
Screening Recommendations for Those with a Family History Colonoscopy screening should begin at 40 years or 10 years earlier than the earliest case of colon cancer in the family.
Genetic testing for Lynch syndrome is typically not recommended for children younger than 18 but can be considered once your children docHub adulthood.
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Colon Cancer Facts One in 18 individuals (5.5 percent) will develop colon cancer in their lifetime. Of all colon cancer cases, only about 5 to 10 percent are hereditary, linked to gene mutations inherited from ones mother or father.
The most common inherited syndromes linked with colorectal cancers are Lynch syndrome (hereditary non-polyposis colorectal cancer, or HNPCC) and familial adenomatous polyposis (FAP), but other rarer syndromes can increase colorectal cancer risk, too.
ing to GI Alliance, Cologuard can miss up to 8% of colon cancer and more than 50% of pre-cancerous polyps. Stool DNA (Cologuard) testing is designed to detect and not prevent cancer. A colonoscopy is the only test that both detects and prevents colon cancer.

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