SKIP to item 7 - Centers for Disease Control and Prevention - cdc 2025

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Treatment for uncomplicated urogenital chlamydia infection is with azithromycin. Doxycycline is an alternative, but azithromycin is preferred as it is a single-dose therapy.
The Centers for Disease Control and Prevention (CDC) collaborates to create the expertise, information, and tools that people and communities need to protect their health through health promotion, prevention of disease, injury and disability, and preparedness for new health threats.
Both the Worldwide Health Organization (WHO) and Centers for Disease Control and Prevention (CDC) recommend either azithromycin or doxycycline as first-line treatments for chlamydia. Though both are effective, the CDC notes that doxycycline may be slightly more effective.
However, in July 2021, due to growing evidence of inferiority of single-dose azithromycin for extragenital infections,4 the CDC updated chlamydia treatment guidelines recommending the multidose doxycycline (100 mg twice daily for 7 days) as the preferred regimen and classifying azithromycin as an alternative.
The CDCs mission is to protect America from health, safety and security threats, both foreign and in the U.S. Whether diseases start at home or abroad, are chronic or acute, curable or preventable, human error or deliberate attack, CDC fights disease and supports communities and citizens to do the same.
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All 11- to 12-year-old adolescents should receive a MenACWY vaccine. Since protection wanes, CDC recommends a MenACWY booster dose at age 16 years. The booster dose provides protection during the ages when adolescents are at highest risk.
Recommended Regimens for Chlamydial Infection Among Adolescents and Adults. Doxycycline 100 mg orally 2 times/day for 7 days. Recommended Regimen for Chlamydial Infection During Pregnancy. Azithromycin 1 g orally in a single dose. Recommended Regimen for Chlamydial Pneumonia Among Infants.
The recommended treatment for gonorrhea is ceftriaxone monotherapy given intramuscularly, with dosing based on the patients body weight. For chlamydia, doxycycline is the preferred treatment. A test-of-cure is recommended for all cases of pharyngeal gonorrhea and for chlamydia if treated with azithromycin.

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