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The WHO rabies exposure categories are: Category I touching or feeding animals, animal licks on intact skin (no exposure); Category II nibbling of uncovered skin, minor scratches or abrasions without bleeding (exposure); Category III single or multiple transdermal bites or scratches, contamination of mucous membrane or Rabies vaccines and immunoglobulins: WHO position April World Health Organization pp-rabies-summary-2018 World Health Organization pp-rabies-summary-2018 PDF
As the disease progresses, the person may experience delirium, abnormal behavior, hallucinations, hydrophobia (fear of water), and insomnia. The acute period of disease typically ends after 2 to 10 days. Once clinical signs of rabies appear, the disease is nearly always fatal, and treatment is typically supportive. What are the signs and symptoms of rabies? - CDC cdc.gov rabies symptoms cdc.gov rabies symptoms
The WHO rabies exposure categories are: Category I touching or feeding animals, animal licks on intact skin (no exposure); Category II nibbling of uncovered skin, minor scratches or abrasions without bleeding (exposure); Category III single or multiple transdermal bites or scratches, contamination of mucous membrane or
Exposure is defined as any situation where saliva or central nerv- ous system tissue of a suspect rabid animal enters an open, fresh wound or comes in contact with a mucus membrane by entering the eye, nose or mouth. The most efficient route of exposure is a bite.
Common physical examination findings of rabies include hyperpyrexia alternating with hypothermia, tachycardia, respiratory collapse, hypersalivation, lacrimation, sweating, dilatation of the pupils and bradycardia. Skin findings may include percussion myoedema, bite marks and bruises.

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Two types of vaccines to protect against rabies in humans exist - nerve tissue and cell culture vaccines. WHO recommends replacement of nerve tissue vaccines with the more efficacious, safer vaccines developed through cell culture as soon as possible. Rabies vaccines - Control of Neglected Tropical Diseases who.int vaccinations-and-immunization who.int vaccinations-and-immunization
Category I includes contact but non-RABV exposure, such as licks on intact skin or touching an animal determined to be rabid (without any break in the skin). Care is performed by washing of the affected areas without any need for a rabies vaccine or other biologics. Time to Revise the WHO Categories for Severe Rabies Virus National Institutes of Health (.gov) articles PMC9146666 National Institutes of Health (.gov) articles PMC9146666
The rabies post-exposure risk assessment tool is designed to determine if post-exposure prophylaxis (PEP) is needed for an individual who was potentially exposed to rabies from contact with an animal. PEP is a series of shots, typically given in the arm similar to a flu shot, given as prevention of rabies.

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