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Your doctor may test your blood to check if there is enough antifungal medication in your body. Depending on the severity of the infection and your immune system, the length of treatment can range from six months to one year.
Healthcare providers use medical and travel history, symptoms, physical examinations, and laboratory tests to diagnose blastomycosis. They will likely test for blastomycosis by taking a blood sample or a urine sample and sending it to a laboratory.
How to Test for Blastomycosis. We recommend ordering an enzyme immunoassay (EIA) urine antigen test initially for blastomycosis diagnosis. EIA urine antigen tests may have the highest sensitivity of noninvasive tests and the quickest turnaround time.
After initial pulmonary infection, hematogenous dissemination of the yeast form of Blastomyces is common. Most often this is manifested by cutaneous lesions, but osteoarticular, genitourinary, and central nervous system (CNS) involvement also occurs.
We Recommend Send both urine and serum for diagnosis of blastomycosis. Test urine for antigen. If the urine antigen is negative but blastomycosis is still suspect, test the serum for Blastomyces IgG antibody which may provide laboratory confirmation of the diagnosis.

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Not all patients with Blastomycosis require treatment. Occasionally the symptoms from Blastomycosis may go away without treatment. People with evidence of Blastomycosis spreading beyond the lungs, or whose symptoms do not improve, will require treatment.
Treatment of blastomycosis requires long-term antifungal medications (i.e. average 2-6 months of therapy). Itraconazole or fluconazole are most commonly used. Some dogs may need to be hospitalized initially to help control some of their more severe symptoms.
Not all patients with Blastomycosis require treatment. Occasionally the symptoms from Blastomycosis may go away without treatment. People with evidence of Blastomycosis spreading beyond the lungs, or whose symptoms do not improve, will require treatment.

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