Blastomycosis Case Worksheet 2025

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Case counts for blastomycosis show a yearly incidence (infection rate) of 2 cases per 100,000 population. The estimated annual death rate among hospitalized patients for blastomycosis usually ranges from 8%-10%, although it increased to 17% in 2021.
In areas where Blastomyces is common in the air, it may not be possible to avoid exposure. People who have weakened immune systems should consider avoiding activities that involve disrupting soil. Some ways to help reduce risk include: Stay inside in windy, dusty conditions.
This disease is rare and mostly affects those who are involved in outdoor activities, as the fungus Blastomyces dermatitidis, is found in moist soil of rotting plants, leaves or wood. People can get blastomycosis by disturbing infected soil or plants, which releases tiny spores into the air.
It is most common around the Ohio and Mississippi River valleys, Great Lakes, Saint Lawrence River, and western United States.
Symptoms and radiographic findings for chronic pulmonary blastomycosis are non-specific and can mimic other diagnoses such as lung neoplasm or tuberculosis. Symptoms can include fever, persistent cough, hemoptysis, night sweats, anorexia, weight loss and malaise.
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An estimated 810% of patients hospitalized with blastomycosis die annually in the United States.
Symptoms of blastomycosis usually start between three weeks and three months after breathing in spores. Most infections are in the lungs can cause symptoms of pneumonia.
Blastomycosis is rare. It is found in the central and southeastern United States, and in Canada, India, Israel, Saudi Arabia, and Africa. The key risk factor for the disease is contact with infected soil.

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