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Canine vaccines are available the following diseases: Canine Distemper Virus (CDV) Canine Parvovirus (CPV) Canine Adenovirus (CAV) Canine Leptospira. Canine parainfluenza virus (CPi) Bordetella bronchiseptica (Kennel Cough) Canine Rabies.
Giving a rabies vaccine and Bordetella as well as a combo could mean as many as 9 shots in one day. Some dogs dont survive this. If your dog has a reaction to the combo shot, theres no way to determine which antigen caused the reaction.
Core vaccines are considered vital to all pets based on risk of exposure, severity of disease or transmissibility to humans. For Dogs: Vaccines for canine parvovirus, distemper, canine hepatitis and rabies are considered core vaccines. Non-core vaccines are given depending on the dogs exposure risk.
Canine adenovirus type 2 (CAV-2) is considered a core vaccine, primarily because it is necessary for the prevention of canine adenovirus type 1 (CAV-1) (against which it cross-protects),18 the cause of infectious canine hepatitis, historically recognized as a severe and often fatal disease of canids.
PARAINFLUENZA (CPIV) is one of many viruses that contribute to Canine Infectious Respiratory Disease Complex also known as kennel cough. They will present with dry hacking coughs, eye and nasal discharge. Vaccinating against this virus can decrease the severity of clinical signs in dogs that acquire kennel cough.

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For vaccination of healthy dogs 6 weeks of age or older against canine parvovirus (CPV) and canine parvovirus type 2c (CPV2c). The high-titer, low-passage CPV virus in Vanguard Canine Parvo is highly immunogenic and capable of stimulating active immunity in the presence of maternal antibodies.
The second core vaccine for dogs is often referred to as the DA2PP or DHPP vaccine. This stands for Distemper, Adenovirus Type 2 (Hepatitis), Parvo, and Parainfluenza, meaning that this vaccine is protects against four different diseases. Vaccines are the best way to protect your pet from highly contagious diseases.
(CDV, CAV2, CPiV, CPV vaccine) For vaccination of healthy dogs 6 weeks of age or older against canine distemper virus (CDV), canine adenovirus type 1 (CAV1), canine adenovirus type 2 (CAV2), canine parainfluenza virus (CPiV), canine parvovirus (CPV), and canine parvovirus type 2c (CPV2c).

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