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Tremor, chorea, dystonia and myoclonus are examples of types of dyskinesia which have different mechanisms and modalities of treatment. Tics and stereotypies may also be considered to be related but some experts call these unvoluntary because there is an element of voluntary control.
Tardive dyskinesia is most common in people with schizophrenia and bipolar patients treated with antipsychotic medications but can occur in the setting of any disorder. In addition, the medications that precipitate tardive dyskinesia can also induce parkinsonian symptoms.
Affected individuals show hyperkinesia with orolingual and limb dyskinesia, dystonia, and chorea, or hypokinesia with parkinsonian features, such as bradykinesia, rigidity, and tremor. Other features may include axial hypotonia, pyramidal tract signs, and eye movement abnormalities.
The two major types are parkinsonian dyskinesia (from the administration of dopamine agonists to patients with chronically low endogenous dopamine) and TD (from long-term exposure to dopamine antagonists). Both are probably the result of dopamine receptor hypersensitivity.
Peak Dose Dyskinesia The most common kind of dyskinesias are called peak dose. These occur when the concentration of levodopa in the blood is at its highest usually one to two hours after you take it. This typically matches up with when the medications are working best to control motor symptoms.
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Causes. Dyskinesia is a complication of long-term levodopa use in people who have had Parkinsons for several years. Other risk factors include being younger at diagnosis and using higher amounts of levodopa for longer periods of time.
Peak‐dose dyskinesiasThese are the most common forms of LID and are related to peak plasma (and possibly high striatal) levels of levodopa. They involve the head, trunk, and limbs, and sometimes respiratory muscles.
Some symptoms of dyskinesia may look like: fidgeting. wriggling. swaying of the body. bobbing of the head. twitching. restlessness.

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