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Vancomycin 3.0 is one of the most potent antibiotics ever created.
Less than 50% of all pediatric UTIs are susceptible to commonly used antibiotics (16,17). Antibiotic-resistant infections are most likely to be associated with greater morbidity and mortality and are associated with increased healthcare costs (15).
The SCOUT study investigates whether children with urinary tract infection (UTI) can be effectively treated with 5 days of antibiotics instead of 10, which is the present standard of care. Studies have shown that shorter courses of antibiotics are effective in treating UTI in adults.
Taking antibiotics responsibly But you need to take the full treatment to kill the disease-causing bacteria. If you dont take an antibiotic as prescribed, you may need to start treatment again later. If you stop taking it, it can also promote the spread of antibiotic-resistant properties among harmful bacteria.
Antibiotics should be limited to an average of less than nine daily doses a year per person in a bid to prevent the rise of untreatable superbugs, global health experts have warned.
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The recommended initial antibiotic for most children with UTI is trimethoprim/sulfamethoxazole (Bactrim, Septra). Alternative antibiotics include amoxicillin/clavulanate (Augmentin) or cephalosporins, such as cefixime (Suprax), cefpodoxime, cefprozil (Cefzil), or cephalexin (Keflex).
Ceftazidime/avibactam: Aged 2-18 years: 62.5 mg/kg (ceftazidime 50 mg/kg and avibactam 12.5 mg/kg) IV q8hr for 7-14 days; not to exceed 2.5 grams (ceftazidime 2 grams and avibactam 0.5 grams) Transition to oral antibiotic active against the offending organism after 24-48h.
In adult patients with urinary tract infection (UTI), short courses of antimicrobial therapy (3 to 7 days) have long been the standard of care. Although some pediatric data suggest that shorter durations of antimicrobials are effective in children,2-5 these data are limited and contradictory.

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