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Therapeutics + Diagnostics= Theranostics. Theranostics is a one-two punch against cancer that involves finding cancer cells anywhere in the body and delivering targeted radiation to kill those cells. Positron emission tomography (PET) is used to locate the cancer, followed by an infusion of medicine to destroy it.
Several features make theranostic nanoparticles ideal in biomedical applications, such as targeted rapid delivery, detailed morphological and biochemical characteristics of the targeted site, sufficient drug delivery, no adverse effect on other organs, and fast clearance [16].
Nanoparticles can be channeled in cancer therapy to encapsulate active pharmaceutical ingredients and deliver them to the tumor site in a more efficient manner. This review enumerates various types of nanoparticles that have entered clinical trials for cancer treatment.
Detection through cell surface protein recognition The main method to detect cancer cells relies on binding of nanoparticle probes conjugated with moieties (protein, short peptides, antibodies, oligonucleotide aptamers) to surface markers on cancer cells and on those entering cells and detecting genetic content.
Theranostic nanoparticles combine diagnostic and therapeutic capabilities for more efficient disease management. To facilitate the development of multi-modal formulations, biodegradable polymers have been discovered as essential carriers.
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Theranostics is the term used to describe the combination of using one radioactive drug to identify (diagnose) and a second radioactive drug to deliver therapy to treat the main tumor and any metastatic tumors.
Theranostics methods may be applied in treatment of esophageal cancer, prostate cancer, breast cancer, in treatment of actinic keratosis, actinic cheilitis and Bowens disease and in treatment of basal cell epithelioma and macular degeneration.

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