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Watson and Crick discovered that DNA has a double helix shape, consisting of two polynucleotide chains held together by bonds between complementary bases. DNA replication is semi-conservative: half of the parent DNA molecule is conserved in each of the two daughter DNA molecules.
The model is called a double helix because two long strands twist around each other like a twisted ladder. The rails of the ladder are made of alternating sugar and phosphate molecules. The steps of the ladder are made of two bases joined together with either two or three weak hydrogen bonds.
The order of enzymes in DNA replication include the following: DNA helicase, RNA primase, DNA polymerase, and finally DNA ligase.
DNA ligase joins the Okazaki fragments together into a single DNA molecule. Helicase opens up the DNA at the replication fork. Single-strand binding proteins coat the DNA around the replication fork to prevent rewinding of the DNA. Topoisomerase works at the region ahead of the replication fork to prevent supercoiling.
There were three models for how organisms might replicate their DNA: semi-conservative, conservative, and dispersive.
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Post a Comment: The complete process of DNA Replication involves the following steps: Recognition of initiation point. endonuclease enzyme. Unwinding of DNA. Template DNA. RNA Primer. Chain Elongation. Replication forks.
Step 4: Termination Another enzyme called DNA ligase joins Okazaki fragments together forming a single unified strand. The ends of the linear DNA present a problem as DNA polymerase can only add nucleotides in the 5 to 3 direction. The ends of the parent strands consist of repeated DNA sequences called telomeres.
What is the fourth step in DNA replication? The polymerse creates a new strand that strings nucleotides together.

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