CLABSI - Virginia Department of Health - Commonwealth of 2025

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VDH helps control the spread of communicable diseases. They help locate the source of an outbreak. They also provide vaccines or immunizations to help protect citizens.
Finally, the highest CLABSI risk was associated with internal jugular and femoral sites, while the lowest risk was found with peripherally inserted central catheters (PICCs) [7].
Slide 10. Five Evidence-Based Steps to Prevent CLABSI Use appropriate hand hygiene. Use chlorhexidine for skin preparation. Use full-barrier precautions during central venous catheter insertion. Avoid using the femoral vein for catheters in adult patients. Remove unnecessary catheters.
Once the source of infection is known, antibiotic or anti-fungal medicines will usually be given. Removal of the central line. Central line removal may be needed to treat CLABSI. In some cases, the central line is removed and replaced with a new device, sometimes at a different site.
If central venous catheter infection is strongly suspected, replace catheter and all intravenous fluids, tubing, and caps. Hand Hygiene: Clean hands immediately before and after each episode of patient contact using the correct hand hygiene technique.
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If infection is suspected, notify the healthcare provider immediately. Symptoms may include fever, hemodynamic instability, altered mental status, catheter dysfunction, and clinical signs of sepsis that start immediately after catheter infusion.
The single most crucial step a nurse can take to help prevent central lineassociated bloodstream infections is performing proper hand hygiene. Other interventions focus on dressing management, bathing practices, access of intravenous infusion sets, blood draws, and management of port line occlusions.
Antibiotics used to treat CRBSI include vancomycin, cefazolin, ceftazidime, or tobramycin. An antibiotic ointment can be used on the access site. If the CRBSI is caused by a fungus, an antifungal would be used (instead of an antibiotic), also given intravenously (IV).

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