Transfusion FAQ's - Department of Pathology - Blood Bank 2025

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The blood transfusion procedure begins when an intravenous (IV) line is placed onto the patients body. It is through the IV that the patient will begin to receive the new blood. Depending on the amount of blood, a simple blood transfusion can take between 1-4 hours.
Because tissue oxygen delivery is dependent on hemoglobin and cardiac output, past medical practice has supported the use of the golden 10/30 rule, by which patients are transfused to a hemoglobin concentration of 10 g/dL or a hematocrit of 30%, regardless of symptoms.
The 30-minute rule states that red blood cell (RBC) units left out of controlled temperature storage for more than 30 minutes should not be returned to storage for reissue; the 4-hour rule states that transfusion of RBC units should be completed within 4 hours of their removal from controlled temperature storage.
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People also ask

The threshold for transfusion of red blood cells should be a hemoglobin level of 7 g per dL (70 g per L) in adults and most children.
Questions to ask about blood transfusions Can you tell me more about blood transfusions? How many blood transfusions will I need to have? Will having a blood transfusion affect me later in life? Are there any support organisations in my local area?
The procedure typically takes one to four hours, depending on which parts of the blood you receive and how much blood you need.
All blood products taken from the blood bank must be hung within 30 minutes and administered (infused) within 4 hours due to the risk of bacterial proliferation in the blood component at room temperature.
Blood components must be transfused within 4 hours of issue. If the transfusion is interrupted for any reason, administration must be discontinued after 4 hours even if the transfusion is not complete.

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