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The Mayo Score for ulcerative colitis disease activity provides an assessement of disease severity and can be used to monitor patients during therapy. The score can range from 0-12 with higher scores indicating worse severity.
The Mayo score is one of the most commonly used disease activity indices in placebo-controlled trials in UC. In its complete form, it is composed of four parts: rectal bleeding, stool frequency, physician assessment, and endoscopy appearance. Each part is rated from 0 to 3, giving a total score of 0 to 12.
The Mayo Score for ulcerative colitis disease activity provides an assessement of disease severity and can be used to monitor patients during therapy. The score can range from 0-12 with higher scores indicating worse severity.
Mayo scoring system Each part is rated from 0 to 3, giving a total score of 0 to 12. A score of 3 to 5 points indicates mildly active disease, a score of 6 to 10 points indicates moderately active disease, and a score of 11 to 12 points indicates severely active disease.
A score of 2 is indicative of moderate disease with friability, erosions, complete loss of vascular pattern, and docHub erythema, and a score of 3 indicates ulceration and spontaneous bleeding [26].
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A score of 3 for bleeding required patients to have at least 50% of bowel motions accompanied by visible blood and at least one bowel motion with blood alone.
A score of 2 is indicative of moderate disease with friability, erosions, complete loss of vascular pattern, and docHub erythema, and a score of 3 indicates ulceration and spontaneous bleeding [26].
In the UCEIS strata, UCEIS 01 = remission (as vascular pattern descriptor); UCEIS 24 = mild; UCEIS 56 = moderate; UCEIS 78 = severe ulcerative colitis.
A score of 3 for bleeding required patients to have at least 50% of bowel motions accompanied by visible blood and at least one bowel motion with blood alone.
A score of 3 for bleeding required patients to have at least 50% of bowel motions accompanied by visible blood and at least one bowel motion with blood alone.

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