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Core needle biopsy can be used to check a: Lump that can be felt (palpable mass) Suspicious area that can only be seen on a mammogram or other imaging test (nonpalpable abnormal finding)
A core biopsy is similar to the FNA, but with a larger needle for a larger tissue sample. Punch biopsy. Punch biopsies involve taking a deeper sample of skin with a biopsy instrument that removes a short cylinder, or "apple core," of tissue.
Fine Needle Aspiration: When It's Used A fine needle aspiration is most often done on swellings or lumps located just under the skin. Imaging tests may also discover abnormal spots deeper inside the body. Doctors may recommend fine needle aspiration for areas such as: cysts (fluid-filled lumps)
A core needle biopsy uses a long, hollow tube to obtain a sample of tissue. Here, a biopsy of a suspicious breast lump is being done. The sample is sent to a lab for testing and evaluation by doctors, called pathologists. They specialize in analyzing blood and body tissue.
Fine needle aspiration of breast masses is a type of biopsy performed using a small needle to obtain samples of tissue and fluid from solid or cystic breast lesions. It is one of the many different modalities for diagnosing breast masses.

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Core needle biopsy uses a hollow needle to remove samples of tissue from the breast. It's the standard and preferred way to diagnose breast cancer. (It may also rule out breast cancer.) A pathologist studies the tissue samples under a microscope to see if they contain cancer.
This is often the preferred type of biopsy if breast cancer is suspected, because it removes more breast tissue than a fine needle aspiration (FNA), but it doesn't require surgery. During this procedure, the doctor uses a hollow needle to take out pieces of breast tissue from the area of concern.
The purpose of a core biopsy is to remove one or more small pieces of tissue from the area of the breast being checked. The breast tissue is then studied under a microscope. This test can help doctors find out the nature of the breast changes.
The most common types include: (1) incisional biopsy, in which only a sample of tissue is removed; (2) excisional biopsy, in which an entire lump or suspicious area is removed; and (3) needle biopsy, in which a sample of tissue or fluid is removed with a needle.
The removal of a tissue sample with a wide needle for examination under a microscope. Also called core needle biopsy.